Danila goes to his successful brother, Victor, in Petersburg to start a new life. Unknown to Danila, Victor is a contract killer, but is in hiding after asking for too much money to assassinate a Chechen mob boss. To avoid exposure, Victor convinces Danila to kill the boss instead.
It is the future, the world is in ruins and a large portion of the population consists of deformed mutants living in reservations. In this world a man decides to spend his vacation visiting the ruins of a museum that is now buried under the sea.
While returning to Leningrad from a visit to his brother, Professor Artyom's car breaks down and he finds assistance at an isolated farmhouse occupied by Alexey, his wife, a Vietnamese laborer, and a stranger who wanders around the farm. When his car is repaired, Artyom leaves, drunk on moonshine, and students Valera and Angelika arrive. After Valera gets drunk, the stranger abducts Angelika.
