A group of people are gathered in a room, which is a "live" depiction of a typical Internet chat room. Some pretends to be much younger than they are, to chat up minors. Two of them falls victim of their own scam in a surprising way.
In an Illinois farming community, Lyle lives quietly with his wife Amy. But their life is set spinning when Lyle's friend Vernon visits with his girlfriend Juliette. Soon Lyle and Juliette have embarked on a passionate affair which has the town talking and the religious community frowning.
In the unreal world of Sacred Heart Hospital, John "J.D." Dorian learns the ways of medicine, friendship and life.
