Ramón Sampedro is a ship mechanic and part-time poet left a quadriplegic following a diving accident. Ramón fought for 30 years for the legal right to end his own life. He develops close relationships with his long-term lawyer Julia and his friend Rosa, who tries to convince him that his life is worth living. Despite his situation, Ramón manages to inspire those around him to live life to the fullest.
In Madrid, Spain, a mysterious serial killer ruthlessly murders his victims by recreating the first appearance of several comic book superheroes. Cosme, a veteran police inspector who is about to retire, works on the case along with the tormented inspector David Valentín and his own son Jorge Elías, a nerdy young man who owns a comic book store.
Madrid, Spain, 1998. The many resources and skills of Gloria, Paz and Sagrario, three middle-aged women investigating paranormal events, are put to the test when their leader, Father Pilón, has an unpleasant encounter.