Lester Burnham, a depressed suburban father in a mid-life crisis, decides to turn his hectic life around after developing an infatuation with his daughter's attractive friend.
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
Charlie is a non-traditional therapist specializing in anger management. He has a successful private practice and he performs pro bono counseling for an inmate group at a state prison. Prior to his career as a therapist, he was a major league baseball player whose career was put on the shelf for good by his own struggle with anger issues.