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In the 17th century, two Portuguese Jesuit priests travel to Japan in an attempt to locate their mentor, who is rumored to have committed apostasy, and to propagate Catholicism.
In 2012, Atsuya and his 2 childhood friends do something bad and run into an old general store. They decide to stay there until the morning. Late into the night, Atsuya sees a letter in the mailbox. The letter is addressed to the Namiya General Store and the letter was written by someone to consult about worries. Incredibly, the letter was written 32 years ago. The mailbox is somehow connected to the year 1980. Atsuya and his friends decide to write a reply and place their letter in the mailbox.
Maya is a photographer. She takes photos related to the eyeball. Kunio is a neurosurgeon and an independent documentary film director. He is interested on making a documentary about Maya. A mysterious eyeball collector watches for Maya's own eyeballs.
When fourteen-year-old Yo is hospitalized she gradually develops feelings for Yayoi who is a nurse tending her. However, Yayoi leaves the nursing profession in favour of prostitution. Yo is disappointed, but turns to the older woman after she is the subject of unrequited love from her mother's man. The two grow closer and Yo is about to find out what motivates Yayoi.
