End of Innocence is a two-part television film that focuses on the work of the German Uranium Association during World War II. At Farm Hall in England, the ten German nuclear scientists interned there as part of Operation Epsilon learn of the dropping of the first atomic bomb on Hiroshima in August 1945. In flashbacks, the development of the German uranium project is recapitulated chronologically from the discovery of nuclear fission by Otto Hahn to the work of Kurt Diebner at the Heereswaffenamt to the experiments of the Kaiser Wilhelm Institute for Physics under Werner Heisenberg and Carl Friedrich von Weizsäcker at the Haigerloch research reactor in spring 1945.
The intellectual Willie flees from his bourgeois-academic environment, leaving behind his wife, child, and job to lead a vagabond life. In Vienna, he meets the retired laborer Josef, who becomes his closest friend. Together, they drink and roam the city. Willie makes one last attempt to visit his ex-wife in Salzburg, but she turns him away. Secretly, he takes his son Tommi with him, putting him in danger when they encounter a sinister motorcycle gang.
Berlin's theatre crowd is excited about the new operetta "Frau Luna". But for the head of the city's vice police, who was invited to the dress rehearsal, the costumes for the ladies onstage are a bit too revealing. He demands the show be cancelled as offensive. The president of the Thusneldenbund has taken it upon himself to alert everyone about the growth of immorality in the capital. The theatre director Knopp has come up with an idea to convince these "fine" gentlemen to let the operetta go onstage again: He intends to win over the friendship of the moral police and then nothing will stand in the way of "Frau Luna" once more being performed.
