Al is concerned for his sister Edie, who starts to realize she's missing something meaningful in her free-spirit lifestyle.
Celestine gets hooked on a new dangerous drug, Nepenthe, and is visited by a mysterious woman named Irene who subtly pushes her towards madness. Meanwhile, Bob and his friends try to save Celestine from her newfound insanity.
In the near future, mental time traveling will be invented. A hitman will use this untested technology to prevent the murder of an innocent person caused by a conflicted gangster.