Paris, Kingdom of France, August 18, 1572. To avoid the outbreak of a religious war, the Catholic princess Marguerite de Valois, sister of the feeble King Charles IX, marries the Huguenot King Henry III of Navarre.
Antoine is a failed and depressed writer. Fred doesn't do much in his life and seems to be happy about it. The two of them share an apartment and live in a shambles. The adventures and mostly the misadventures of these two buddies/losers, makes them realise that despite everything that happens their friendship is the most important thing in their lives.
When the mother of a "tribe" of five children leaves for good, their inept father is not sure how to keep the family clothed and fed, and without the help of his neighbor Simone, he would be nowhere. She is attracted to him but eventually gives up on the relationship. Meanwhile, the father grabs his brood and they take off for Paris in search of the wife. But Simone accidentally ends up on the same train...