Ferdinando Cefalù is desperate to marry his cousin, Angela, but he is married to Rosalia and divorce is illegal in Italy. To get around the law, he tries to trick his wife into having an affair so he can catch her and murder her, as he knows he would be given a light sentence for killing an adulterous woman. He persuades a painter to lure his wife into an affair, but Rosalia proves to be more faithful than he expected.
Bill Meceita, a boy whose family was murdered in front of him by a gang, sets out 15 years later to exact revenge. On his journey, he finds himself continually sparring and occasionally cooperating with Ryan, a gunfighter on his own quest for vengeance, who knows more than he says about Bill's tragedy.
Don Camillo (now bishop) and Peppone (now senator) return to the town of Brescello and rekindle their friendly rivalry.
