French nuclear tests irradiate an iguana into a giant monster that viciously attacks freighter ships in the Pacific Ocean. A team of experts, including Niko Tatopoulos, conclude that the oversized reptile is the culprit. Before long, the giant lizard is loose in Manhattan as the US military races to destroy the monster before it reproduces and it's spawn takes over the world.
Chris crashes into a carload of other young people, and the group of stranded motorists is soon lost in the woods of West Virginia, where they're hunted by three cannibalistic mountain men who are grossly disfigured by generations of inbreeding.
A man and his buddies learn to deal with love, sex, and passing gas.
