A young woman inherits an old hotel in Louisiana where, following a series of supernatural "accidents", she learns that the building was built over one of the entrances to Hell.
After a doctor kills his mistress and himself while researching the mysterious previous owner of his Boston home, his colleague, Dr. Norman Boyle, takes over his studies and moves his family into the Boston mansion. Soon after, Boyle's young son Bob becomes plagued by visions of a young girl, who warns him of the danger within the house.
A burned-out New York police detective teams up with a college psychoanalyst to track down a vicious serial killer randomly stalking and killing various young women around the city.
