In the second episode of the trilogy Fantômas kidnaps distinguished scientist professor Marchand with the aim to develop a super weapon that will enable him to menace the world. Fantômas is also planning to abduct a second scientist, professor Lefebvre.
In this Franco-Italian gangster parody, a shopkeeper on his way to an Italian holiday suffers a crash that totals his car. The culprit can only compensate his ruined trip by driving an American friend's car from Naples to Bordeaux, but as it happens to be filled with such contraband as stolen money, jewelry and drugs, the involuntary and unwitting companions in crime soon attract all but recreational attention from the "milieu".
Alphonse Tram is unwittingly involved in several murders despite having no memory of committing the crimes. His confusion lead him to confess to his neighbour, Inspector Morvandieu. Alphonse and Morvandieu become the axis around which murders occur.
