A man suffers from the curse of lycanthrope and seeks help from doctor and wife team. They both turn out to be vampires and end up dueling it out with the werewolf star.
A group of international criminals steal a large emerald from a heavily guarded Colombian mine and they plan to sell it on the black market. Unfortunately, the evil Dr. Igor is also manipulating other criminals, as well as the ones who stole the emerald, for his own benefit. Santo, a Mexican wrestler/Interpol agent works with the Colombian authorities in an attempt to recover the emerald and to stop Dr. Igor and his subordinates, as well.
The same day of their marriage, Jean's wife dies of a strange ailment in the middle of surgery. Afflicted by the loss, the young man abandons his medical studies and takes refuge in the memories of his time of courtship. At the same time that this happens, a wave of murders shakes the city with the same pattern of behavior: the victims are surgery students whose bodies have had both hands amputated.
