Semiramis, a powerful and beautiful Assyrian queen, oversees the construction of the luxurious city of Babylon. She falls in love with Kir, a fallen prince turned into a slave who corresponds to her love. But a palace conspiracy will make the two lovers separate and confront each other.
Noble, wise King Sardanapolo and his more soft and naive younger brother Prince Sammash get into a bitter feud over the affections of sweet and alluring innocent peasant girl Mirra. Meanwhile, the treacherous and ruthlessly ambitious General Arbace plots against both siblings.
