Tom and Jerry two Italian two bit actors go to America because they hope to take part in a film starring Sylvester Stallone. However when they go to his villa in Beverly Hills, Stallone gets murdered and the two are suspected of the murder. Hunted by the CIA and the FBI they flee across the USA disguised as women and end up working in a restaurant as showgirls. Here Tom meets a Mafia boss who falls in love with him and goes to Mexico with him to escape the police hunt. Some years later the two friends meet again: Tom has married the boss's ex girlfriend even if he still dresses as a woman.
Giovanna Dei, a young cartoonist, works on the violent comic strip "Doctor Dark". Unfortunately, young women are being killed in the style of the comic strip character and she becomes the main suspect.
Police Comissioner Datti is investigating the murder of a female doctor whose murderer seems to be a thirty-fivish year old man. Soon another murder follows: Pianist Robert Dominici's girlfriend is found killed. The killer also challenges Datti on the phone and says he can't be caught since he has a secret which makes him invulnerable. In the meantime the clues seems to point in strange directions...
