A cross-dressing farce, adapted from "Madame Lucy" by Jean Arlette, in which to help a friend in a lawsuit, Jack Mitchell disguises himself as the mysterious "Madame Brown," a missing witness important to the case of the plaintiff. He attracts the romantic attention of two old roués and one hot Broadway showgirl.
Charley Wyckham and Jack Chesney pressure fellow student Fancourt Babberly to pose as Charley's Brazilian Aunt Donna Lucia. Their purpose is to have a chaperone for their amorous visits with Amy and Kitty, niece and ward of crusty Stephen Spettigue. Complications begin when Fancourt, in drag, becomes the love object of old Spettigue and Sir Francis Chesney.
Jim Wilson is separated from his wife Bella, so when his maiden Aunt Selina -- who thoroughly disapproves of divorce -- comes to visit, Wilson is compelled to locate a temporary wife. His friend, Kit Eclair, is happy to fill in, but during a party, his home is quarantined for smallpox. To complicate matters, a burglar is hiding from a cop in Wilson's home, and wacky Anne Brown is busy trying to hold a seance.
