A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
Deranged scientist, Gustav Niemann, escapes from prison and overtakes the director of a traveling chamber of horrors, soon reviving the infamous Count Dracula, the frozen Frankenstein Monster, and the Wolf Man.
During the Klondike Gold Rush, a misanthropic cattle driver and his talkative elderly partner run afoul of the law in Alaska and are forced to work for a saloon owner to take her supplies into a newly booming but lawless Candian town.
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Handsome Stranger has agreed to escort Charming Jones to collect her inheritance from her father. But Avery Simpson wants the money and hires notorious outlaw Cactus Jack to ambush Charming. However, Cactus Jack is not very good at robbing people.
Rabbi Avram arrives in Philadelphia from Poland en route to San Francisco where he will be a congregation's new rabbi. An innocent and inexperienced traveller, he is tricked by con men to pay for the trip to go west, then they leave him and his belongings scattered along a deserted road. He is befriended by a stranger, Tommy, who is a bank robber and have many adventures during their journey.