An American nurse living and working in Tokyo is exposed to a mysterious supernatural curse, one that locks a person in a powerful rage before claiming their life and spreading to another victim.
In town for a job interview, a young woman arrives at her Airbnb late at night only to find that it has been mistakenly double-booked and a strange man is already staying there. Against her better judgement, she decides to stay the night anyway.
Henry, a newly resurrected cyborg who must save his wife/creator from the clutches of a psychotic tyrant with telekinetic powers, AKAN, and his army of mercenaries. Fighting alongside Henry is Jimmy, who is Henry's only hope to make it through the day. Hardcore Henry takes place over the course of one day, in Moscow, Russia.
