Giacinto lives with his wife, their ten children and various other family members in a shack on the hills of Rome. Some time ago he has lost his left eye while at work, and got a consistent sum of money from the insurance company, which he keeps hidden from the rest of the family. His whole life is now based on defending the money he sees as his own, while the rest of the family tries to kill him.
Christmas holidays on the snow of Cortina D'Ampezzo. Mario, a guy from Rome who has not much money, falls in love with the American Samantha, the girlfriend of hypochondriac Roberto. Billo, a singer and a playboy, meets Ivana: she's married with a rich man, Donatone, but in the past she had a flirt with Billo, who wants to reignite the flame.
This time the "amici" (friends) are just four: Necchi, Meandri, Mascetti and Sassaroli. Nevertheless they are older they still love to spend their time mainly organizing irresistible jokes to everyone in every kind of situation. Mascetti is hospitalized in a geriatric clinic. Of course the place become immediately the main stage for all their jokes. After some jokes they decided to place an ultimate incredible and farcical joke to the clinic guests.
