Agnes and her two sisters struggle through a day in a home overrun by gamblers, thieves, and johns.
After resolving a situation of exorcism, the half-breed demon hunter Jake Greyman (Sean Patrick Flanery) reports to Cardinal White (William Bassett) and they realize that the demon Asmodeus (Billy Drago) is impregnating many mortals trying to raise offspring. Cardinal White calls Sister Sarah Ryan (Colleen Porch) to assist Jake in his hunting for Asmodeus and his women.
A troubled young boy and his father on a road trip stumble upon a rural farm where the elderly owner has sinister plans for the both of them involving witchcraft and evil.
