Canelo Alvarez takes on WBO light heavyweight champion Sergey Kovalev at the MGM Grand Garden Arena in Paradise, Nevada.
Vasyl Lomachenko (12-1, 9 KOs) defends his WBA and WBO lightweight titles against England's Anthony "Million Dollar" Crolla (34-6-3, 13 KOs) at the Staples Center in Los Angeles.
Former two-weight world champion Luis Nery looks to take a step towards another world title shot when he takes on Armenia's Azat Hovhannisyan.