John Drury saves Duke, a wild horse accused of murder, and trains him. When he discovers that the real murderer, a bad guy known as The Hawk, is the town's leading citizen, Drury arrested on a fraudulent charge.
The Three Mesquiteers convince a group of settlers to exchange their present property for some which, unbeknownst to our goodguys, is going to be worthless. They are captured before they can warn the ranchers.
In 1889 pioneers race ahead of the law to claim free land in Oklahoma, forming wide-open towns. In one such, citizens elect Milt Dawson to challenge the self-appointed rule of gambler Ace Holmes, only to have him shot in the back. But leading the next batch of settlers is Milt's quick-on-the-draw son John, who gets help from friendly outlaws.