A mild-mannered gay dentist and a womanizing bar owner rekindle their unlikely friendship when, upon meeting by chance after a decade apart, the latter turns out to be severely ill.
Deuce Bigalow goes to Amsterdam after a little accident including two irritating kids and a bunch of aggressive dolphins. There he meets up with his old friend T.J. Hicks. But a mysterious killer starts killing some of Amsterdam's finest gigolos and T.J. is mistaken for the extremely gay murderer. Deuce must enter the gigolo industry again to find the real murderer and clear T.J.'s name.
When extreme weather suddenly hits the Netherlands in 1963, a 120-mile tour skating event taking place on natural ice forces its contestants to contend with life-threatening race conditions.