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An adventurer (Hamilton) decides to go in search of the Lost City in the Amazon jungle. A motley crew of other people decide to join him for the wealth of the city, for reasons of their own. But to their horror they find out that they have bitten off more than they can chew, what with a Nazi doctor still using the place for his human experiments.
James Brown III, also known as Secret Agent 00 Soul, is an elite international operative who finally tells off the government and fulfills his longtime dream of opening a detective agency in his hold neighborhood. His once plush workspace is no a ramshackle hole-in-the-wall above a chicken and ribs joint, and instead of being surrounded by glamourous female agents, the is being shaken down by his son Junior, a 400-pound ne'er-do-well who wouldn't know hard work if it hit him in the face. Nonetheless, 00 Soul is able to transform an unlikely bunch of misfits into the wackiest group of oddball detectives ever to hit the 'hood.
The "Satans" are a very cruel biker gang led by Anchor. The gang goes to a diner in the middle of nowhere in the California desert where they begin to terrorize Lew and his patrons and his waitress, Tracy. After a little killing, one of the patrons named Johnny manages to escape from the bikers into the desert. They need to reach a town before the Satans catch up to them and kill them.
