The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.
Fred Engel's father is murdered by Colonel Brinkley in order to acquire a treasure map, however the Colonel only acquires half of it, the other half as held by Mrs. Butler. Discovering the scene of the crime, Old Shatterhand and Winnetou help Fred bring his father's murderer to justice and locate the treasure of Silver Lake.
An army gold shipment and its escort vanish in the Ozarks, prompting accusations of theft and desertion but frontiersman Old Shatterhand and Apache chief Winnetou help solve the mystery of the missing army gold.
