Six young friends in the small town of Angamaly tries their luck by starting a pork business lead by Vincent Pepe. They initially strike a business deal with Rajan and Ravi despite the duo having killed a close friend of theirs in a gang fight. Vincent is in love with Sakhi and plan to immigrate abroad with her. But their plans hit a road bump as the deal with the gangsters hits some road bumps.
Jaison, a teenager, has a crush on Keerthy, but she does not reciprocate his feelings. To make things worse, he gets in trouble with Ravi, the new teacher who is liked by everyone, especially Keerthy.
Manjummel Boys, based on a real story, is about a bunch of friends who set out on a trip to Kodaikanal and the events that occur there.
