A Pennsylvania band scores a hit in 1964 and rides the star-making machinery as long as it can, with lots of help from its manager.
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
When the Universe decides what it wants, it's pointless to resist. With his family's life at stake, Joseph Steadman finds himself the unwilling test subject of a maniacal scientist in a battle that could save the world – or destroy it.