Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
A man and a young woman have a chance encounter at a laundry mat which leads to a story about a birthday party where everyone has been killed by a madman in a white jumpsuit.
Follow the investigations of a team of NYPD forensic scientists and police officers identified as "Crime Scene Investigators".
