An ex-fighter pilot forced to take over the controls of an airliner when the flight crew succumbs to food poisoning.
A cross-country road race is based on an actual event, the Cannonball Baker Sea to Shining Sea Memorial Trophy Dash, organized by Brock Yates to protest the 55 mph speed limit then in effect in the U.S. The Cannonball was named for Erwin G. "Cannonball" Baker, who in the roaring 20's rode his motorcycle across the country. Many of the characters are based on ruses developed by real Cannonball racers over the several years that the event was run.
During his long career, bounty hunter Ralph "Papa" Thorson has caught over 5,000 criminals. Now, while he is working on apprehending fugitives in Illinois, Texas and Nebraska, he himself is being hunted by a psychotic killer.