Hillary and Bonnie meet one morning by the side of the road. They become fast friends, share their secrets, and, on a rising wave of frenzy, later that afternoon, murder an old woman. They did it, they say later, for fun.
Eli is a burglar who is caught in the act by Twinkle, an heiress who coerces him into a sexual relationship. Their violent break-up makes him a fugitive in search of a new identity. He lands in a trashy trailer park where he touches the lives of several dysfunctional residents.
ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.