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A British woman visits her husband at the Mexican mine he is attempting to reopen and discovers that the workers refuse to enter the mine, fearing an ancient curse. The couple enter the mine to prove there is no danger and inadvertently release a demon which possesses people's left hands and forces them to behave in a suitably diabolical manner.
Corporate smuggling of South American killer bees into the United States results in huge swarms terrorizing the northern hemisphere. A small team of scientists work desperately to destroy the threat, but the bees soon mutate into a super-intelligent species that threatens the world.
Two clumsy and absent-minded spies (Capulina and Chespirito) are hired to save the world from a nuclear attack.
Brother and sister Enrique and Rosa flee persecution at home in Guatemala and journey north, through Mexico and on to the United States, with the dream of starting a new life.
