A gangster known as "Samurai" wants to turn the waterfront of Rome into a new Las Vegas. All the local mob bosses have agreed to work for this common goal. But peace is not to last long.
The charismatic criminal Dobermann, who got his first gun when he was christened, leads a gang of brutal robbers. After a complex and brutal bank robbery, they are being hunted by the Paris police. The hunt is led by the sadistic cop Christini, who only has one goal: to catch Dobermann at any cost.
Milan, Italy, 1967. Santo Russo, a boy of Calabrian origin, arrives north with his parents and younger brother to find better living conditions. Due to an absurd misunderstanding and his father's contempt, Santo ends up in prison, where he gets a “true education.” In 1978, he and his friends Slim and Mario embark on a 15-year criminal career, a successful and ruthless spiral of robberies, kidnappings, murders and heroin smuggling.
